Hydrochloric Acid → 6-bromo-5-hydroxy-4-(trifluoromethyl)-1H-quinolin-2-one
Reaction equation
[Br:24][N:25]1[C:26](=[O:27])[CH2:28][CH2:29][C:30]1=[O:31].[CH3:33][CH2:34][O:35][C:36]([CH3:37])=[O:38].[CH:17]([NH:18][CH:19]([CH3:20])[CH3:21])([CH3:22])[CH3:23].[ClH:32].[OH:1][c:2]1[c:3]2[c:4]([C:13]([F:14])([F:15])[F:16])[cH:5][c:6](=[O:12])[nH:7][c:8]2[cH:9][cH:10][cH:11]1>>[OH:1][c:2]1[c:3]2[c:4]([C:13]([F:14])([F:15])[F:16])[cH:5][c:6](=[O:12])[nH:7][c:8]2[cH:9][cH:10][c:11]1[Br:24]Participants
6
Sources & evidence
- ORD record
- ord-ee50fc02821a4f2680ef0527125237bc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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