Bromide ion → 3,4-dihydro-7-methoxy-3-(1-phenylmethyl-4-piperidinyl)-2(1H)-quinazolinone
Reaction equation
[Br-:31].[C:33]([O:34][CH3:35])([CH3:36])([CH3:37])[CH3:38].[CH3:25][N:26]([CH:27]=[O:28])[CH3:29].[K+:32].[NH2:1][c:2]1[c:3]([CH2:4][NH:5][CH:6]2[CH2:7][CH2:8][N:9]([CH2:12][c:13]3[cH:14][cH:15][cH:16][cH:17][cH:18]3)[CH2:10][CH2:11]2)[cH:19][cH:20][c:21]([O:23][CH3:24])[cH:22]1.[OH2:30]>>[NH:1]1[c:2]2[c:3]([cH:19][cH:20][c:21]([O:23][CH3:24])[cH:22]2)[CH2:4][N:5]([CH:6]2[CH2:7][CH2:8][N:9]([CH2:12][c:13]3[cH:14][cH:15][cH:16][cH:17][cH:18]3)[CH2:10][CH2:11]2)[C:27]1=[O:28]Participants
7
Sources & evidence
- ORD record
- ord-36c9781cae474e89910675aec66a5e03
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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