Water → ethyl 4-(5-chloropyrazin-2-yl)-2-[4-[(3,4-dichloro-5-methyl-1H-pyrrole-2-carbonyl)amino]-3-methylpiperidin-1-yl]-1,3-thiazole-5-carboxylate
Reaction equation
[Br:1][c:2]1[s:3][c:4]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[c:5](-[c:7]2[n:8][cH:9][c:10]([Cl:13])[n:11][cH:12]2)[n:6]1.[CH3:47][N:48]1[CH2:49][CH2:50][CH2:51][C:52]1=[O:53].[CH:37]([N:38]([CH2:39][CH3:40])[CH:41]([CH3:42])[CH3:43])([CH3:44])[CH3:45].[Cl:19][c:20]1[c:21]([C:27](=[O:28])[NH:29][CH:30]2[CH:31]([CH3:36])[CH2:32][NH:33][CH2:34][CH2:35]2)[nH:22][c:23]([CH3:26])[c:24]1[Cl:25].[OH2:46]>>[c:2]1([N:33]2[CH2:32][CH:31]([CH3:36])[CH:30]([NH:29][C:27]([c:21]3[c:20]([Cl:19])[c:24]([Cl:25])[c:23]([CH3:26])[nH:22]3)=[O:28])[CH2:35][CH2:34]2)[s:3][c:4]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[c:5](-[c:7]2[n:8][cH:9][c:10]([Cl:13])[n:11][cH:12]2)[n:6]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-989217cbc8654f61a29ffb79c6f48a6d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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