Borane → tert-Butyl 4-(hydroxymethyl)-4-(pyridin-3-yl)piperidine-1-carboxylate
Reaction equation
[BH3:28].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([C:14](=[O:15])[OH:16])([c:17]2[cH:18][n:19][cH:20][cH:21][cH:22]2)[CH2:12][CH2:13]1.[F:29][C:30]([F:31])([F:32])[C:33]([OH:34])=[O:35].[O:23]1[CH2:24][CH2:25][CH2:26][CH2:27]1.[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([CH2:14][OH:15])([c:17]2[cH:18][n:19][cH:20][cH:21][cH:22]2)[CH2:12][CH2:13]1Participants
5
Sources & evidence
- ORD record
- ord-f43e604e05be498fb838332b60b8c4fe
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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