Water → 1-Chloro-2-(2,4-difluorophenyl)butane-2,3-diol

HRID 2154284Notes

Reaction equation

[CH2:24]([N+:25]([CH2:26][CH2:27][CH2:28][CH3:29])([CH2:30][CH2:31][CH2:32][CH3:33])[CH2:34][CH2:35][CH2:36][CH3:37])[CH2:38][CH2:39][CH3:40].[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[CH3:42][CH2:43][O:44][C:45](=[O:46])[CH3:47].[Cl:1][CH2:2][C:3]([CH:4]([CH3:5])[O:6][Si:7]([C:8]([CH3:9])([CH3:10])[CH3:11])([CH3:12])[CH3:13])([OH:14])[c:15]1[c:16]([F:22])[cH:17][c:18]([F:21])[cH:19][cH:20]1.[F-:23].[OH2:41]>>[Cl:1][CH2:2][C:3]([CH:4]([CH3:5])[OH:6])([OH:14])[c:15]1[c:16]([F:22])[cH:17][c:18]([F:21])[cH:19][cH:20]1

Participants

Reactant 6

HCID 962Water

HCID 8028Tetrahydrofuran

HCID 8857Ethyl Acetate

HCID 16028Tetrabutylammonium

HCID 28179Fluoride Ion

HCID 231170471-Chloro-2-(2,4-difluorophenyl)-3-(tert-butyldimethylsilyloxy)butan-2-ol

Product 1

HCID 231170401-Chloro-2-(2,4-difluorophenyl)butane-2,3-diol

Sources & evidence

ORD record: ord-b916bd0525b7481aba6f27499089a699
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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