Bicarbonate Ion → N-{4-[(3-Chloro-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]-3-fluorophenyl}-2,2,2-trifluoroacetamide
Reaction equation
[C:33](=[O:34])([OH:35])[O-:36].[Cl:1][N:2]1[C:3](=[O:4])[CH2:5][CH2:6][C:7]1=[O:8].[F:9][C:10]([C:11](=[O:12])[NH:13][c:14]1[cH:15][c:16]([F:30])[c:17]([O:20][c:21]2[c:22]3[c:23]([n:24][cH:25][cH:26]2)[nH:27][cH:28][cH:29]3)[cH:18][cH:19]1)([F:31])[F:32].[Na+:37].[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1>>[Cl:1][c:29]1[c:22]2[c:21]([O:20][c:17]3[c:16]([F:30])[cH:15][c:14]([NH:13][C:11]([C:10]([F:9])([F:31])[F:32])=[O:12])[cH:19][cH:18]3)[cH:26][cH:25][n:24][c:23]2[nH:27][cH:28]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-d7baec29ff1b4f88b41a86ac0c855f45
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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