Hydrochloric Acid → rac-(2R,3S,4R,5S)-3-(3-chloro-2-fluoro-phenyl)-4-(4-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carboxylic acid [1-(2-hydroxy-ethyl)-2-oxo-1,2-dihydro-pyridin-4-yl]-amide
Reaction equation
[C:1]([Si:2]([CH3:3])([CH3:4])[O:6][CH2:7][CH2:8][n:9]1[c:10](=[O:46])[cH:11][c:12]([NH:15][C:16](=[O:17])[CH:18]2[NH:19][CH:20]([CH2:41][C:42]([CH3:43])([CH3:44])[CH3:45])[C:21]([C:31]#[N:32])([c:33]3[c:34]([F:40])[cH:35][c:36]([Cl:39])[cH:37][cH:38]3)[CH:22]2[c:23]2[c:24]([F:30])[c:25]([Cl:29])[cH:26][cH:27][cH:28]2)[cH:13][cH:14]1)([CH3:5])([CH3:47])[CH3:48].[CH2:50]1[O:51][CH2:52][CH2:53][CH2:54]1.[ClH:49]>>[OH:6][CH2:7][CH2:8][n:9]1[c:10](=[O:46])[cH:11][c:12]([NH:15][C:16](=[O:17])[CH:18]2[NH:19][CH:20]([CH2:41][C:42]([CH3:43])([CH3:44])[CH3:45])[C:21]([C:31]#[N:32])([c:33]3[c:34]([F:40])[cH:35][c:36]([Cl:39])[cH:37][cH:38]3)[CH:22]2[c:23]2[c:24]([F:30])[c:25]([Cl:29])[cH:26][cH:27][cH:28]2)[cH:13][cH:14]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-1064cb185ca046088eea36afdf24869a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…