Dichloromethane → {3-[5-(3-Fluorophenyl)-3-isobutyryl-2-phenyl-2,3-dihydro-[1,3,4]thiadiazol-2-yl]-propyl}-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][CH2:9][CH2:10][C:11]1([c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[S:12][C:13]([c:16]2[cH:17][c:18]([F:22])[cH:19][cH:20][cH:21]2)=[N:14][NH:15]1)=[O:29].[C:37]([CH:38]([CH3:39])[CH3:40])(=[O:41])[Cl:42].[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[Cl:43][CH2:44][Cl:45]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][CH2:9][CH2:10][C:11]1([c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[S:12][C:13]([c:16]2[cH:17][c:18]([F:22])[cH:19][cH:20][cH:21]2)=[N:14][N:15]1[C:37]([CH:38]([CH3:39])[CH3:40])=[O:41])=[O:29]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-3019dc6c9c2a40478a394d97112ac498
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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