Potassium Cation → 2-(difluoro(4-fluorophenyl)methyl)-7-fluoro-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine
Reaction equation
[CH3:34][c:35]1[cH:36][c:37]([NH2:40])[n:38][nH:39]1.[CH:25]([N:26]([CH2:27][CH3:28])[CH:29]([CH3:30])[CH3:31])([CH3:32])[CH3:33].[Cl:1][c:2]1[n:3][c:4]([C:13]([c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)([F:21])[F:22])[n:5][c:6]2[cH:7][c:8]([F:12])[cH:9][cH:10][c:11]12.[I-:24].[K+:23].[O:41]=[CH:42][N:43]([CH3:44])[CH3:45].[OH2:46]>>[c:2]1([NH:40][c:37]2[cH:36][c:35]([CH3:34])[nH:39][n:38]2)[n:3][c:4]([C:13]([c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)([F:21])[F:22])[n:5][c:6]2[cH:7][c:8]([F:12])[cH:9][cH:10][c:11]12Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-d8955f7b6b6249ec85cfda07d57e60bb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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