Tetrahydrofuran → N-(3-chloro-5-((3,5-dichloro-2-hydroxy-N-isobutylphenylsulfonamido)methyl)benzyl)-N-isobutylpyridine-3-sulfonamide

HRID 2155558Notes

Reaction equation

HRID 2155558 reaction equation
[CH2:49]1[O:50][CH2:51][CH2:52][CH2:53]1.[CH3:42][CH2:43][N:44]([CH2:45][CH3:46])[CH2:47][CH3:48].[Cl:11][c:12]1[c:13]([OH:41])[c:14]([S:19](=[O:20])(=[O:21])[N:22]([CH2:23][CH:24]([CH3:25])[CH3:26])[CH2:27][c:28]2[cH:29][c:30]([Cl:40])[cH:31][c:32]([CH2:34][NH:35][CH2:36][CH:37]([CH3:38])[CH3:39])[cH:33]2)[cH:15][c:16]([Cl:18])[cH:17]1.[n:1]1[cH:2][c:3]([S:7](=[O:8])(=[O:9])[Cl:10])[cH:4][cH:5][cH:6]1>>[n:1]1[cH:2][c:3]([S:7](=[O:8])(=[O:9])[N:35]([CH2:34][c:32]2[cH:31][c:30]([Cl:40])[cH:29][c:28]([CH2:27][N:22]([S:19]([c:14]3[c:13]([OH:41])[c:12]([Cl:11])[cH:17][c:16]([Cl:18])[cH:15]3)(=[O:20])=[O:21])[CH2:23][CH:24]([CH3:25])[CH3:26])[cH:33]2)[CH2:36][CH:37]([CH3:38])[CH3:39])[cH:4][cH:5][cH:6]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 3164136Pyridine-3-sulfonyl chlorideHCID 585315243,5-Dichloro-N-(3-chloro-5-((isobutylamino)methyl)benzyl)-2-hydroxy-N-isobutylbenzenesulfonamide

Product 1

HCID 44594685N-(3-chloro-5-((3,5-dichloro-2-hydroxy-N-isobutylphenylsulfonamido)methyl)benzyl)-N-isobutylpyridine-3-sulfonamide

Sources & evidence

ORD record
ord-a61f36820b424524b00cc7c5d5cc7edc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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