Thioglycolic Acid → Tert-butyl 3-[cyclopropyl-[[1-(3-methoxypropyl)indol-3-yl]methyl]carbamoyl]-5-[2-(1,3-dioxoisoindol-2-yl)ethylamino]piperidine-1-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([C:40]([N:41]([CH2:42][c:43]2[cH:44][n:45]([CH2:52][CH2:53][CH2:54][O:55][CH3:56])[c:46]3[cH:47][cH:48][cH:49][cH:50][c:51]23)[CH:57]2[CH2:58][CH2:59]2)=[O:60])[CH2:11][CH:12]([N:14]([S:15]([c:16]2[cH:17][cH:18][cH:19][cH:20][c:21]2[N+:22]([O-:23])=[O:24])(=[O:25])=[O:26])[CH2:27][CH2:28][N:29]2[C:30](=[O:39])[c:31]3[cH:32][cH:33][cH:34][cH:35][c:36]3[C:37]2=[O:38])[CH2:13]1.[CH2:66]1[CH2:67][CH2:68][C:69]2=[N:74][CH2:73][CH2:72][CH2:71][N:70]2[CH2:75][CH2:76]1.[O:77]=[CH:78][N:79]([CH3:80])[CH3:81].[OH:61][C:62]([CH2:63][SH:64])=[O:65]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([C:40]([N:41]([CH2:42][c:43]2[cH:44][n:45]([CH2:52][CH2:53][CH2:54][O:55][CH3:56])[c:46]3[cH:47][cH:48][cH:49][cH:50][c:51]23)[CH:57]2[CH2:58][CH2:59]2)=[O:60])[CH2:11][CH:12]([NH:14][CH2:27][CH2:28][N:29]2[C:30](=[O:39])[c:31]3[cH:32][cH:33][cH:34][cH:35][c:36]3[C:37]2=[O:38])[CH2:13]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-1ccf7e5dec354ffb8cd03f202863b088
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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