Water → 1-[(4-Fluorophenyl)(phenyl)methyl]-2-formyl-4,6-dimethyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile
Reaction equation
[CH3:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[CH3:46][N:47]([CH:48]=[O:49])[CH3:50].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[F:19][c:20]1[cH:21][cH:22][c:23]([CH:26]([n:27]2[cH:28][c:29]([C:38]#[N:39])[c:30]3[c:31]2[n:32][c:33]([CH3:37])[cH:34][c:35]3[CH3:36])[c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)[cH:24][cH:25]1.[Li:8][CH2:9][CH2:10][CH2:11][CH3:12].[O:51]1[CH2:52][CH2:53][CH2:54][CH2:55]1.[OH2:56]>>[F:19][c:20]1[cH:21][cH:22][c:23]([CH:26]([n:27]2[c:28]([CH:48]=[O:49])[c:29]([C:38]#[N:39])[c:30]3[c:31]2[n:32][c:33]([CH3:37])[cH:34][c:35]3[CH3:36])[c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)[cH:24][cH:25]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-547ebd81221d431091d479b0ba2f454e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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