Chloride → 3-(4-bromo-2-hydroxyphenyl)-3-hydroxy-1-{[5-(trifluoromethyl)furan-2-yl]methyl}-1,3-dihydro-2H-indol-2-one
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([OH:8])[cH:5][cH:6][cH:7]1.[CH:10]([Mg+:11])([CH3:12])[CH3:13].[Cl-:9].[Cl:40][CH2:41][Cl:42].[F:14][C:15]([c:16]1[cH:17][cH:18][c:19]([CH2:21][N:22]2[C:23](=[O:32])[C:24](=[O:31])[c:25]3[cH:26][cH:27][cH:28][cH:29][c:30]32)[o:20]1)([F:33])[F:34].[O:35]1[CH2:36][CH2:37][CH2:38][CH2:39]1>>[Br:1][c:2]1[cH:3][c:4]([OH:8])[c:5]([C:24]2([OH:31])[C:23](=[O:32])[N:22]([CH2:21][c:19]3[cH:18][cH:17][c:16]([C:15]([F:14])([F:33])[F:34])[o:20]3)[c:30]3[c:25]2[cH:26][cH:27][cH:28][cH:29]3)[cH:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-f3cfc1560bf5469f81674ef94ea9fe7e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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