Dimethylformamide → 2-(4-(2-methylpyridin-4-yl)phenyl)-N-(5-phenylpyridin-2-yl)acetamide

HRID 2158376Notes

Reaction equation

HRID 2158376 reaction equation
[CH3:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([CH2:14][C:15](=[O:16])[OH:17])[cH:12][cH:13]2)[cH:7]1.[CH:31]([N:32]([CH2:33][CH3:34])[CH:35]([CH3:36])[CH3:37])([CH3:38])[CH3:39].[O:40]=[CH:41][N:42]([CH3:43])[CH3:44].[c:18]1(-[c:24]2[cH:25][cH:26][c:27]([NH2:30])[n:28][cH:29]2)[cH:19][cH:20][cH:21][cH:22][cH:23]1>>[CH3:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([CH2:14][C:15](=[O:17])[NH:30][c:27]3[cH:26][cH:25][c:24](-[c:18]4[cH:19][cH:20][cH:21][cH:22][cH:23]4)[cH:29][n:28]3)[cH:12][cH:13]2)[cH:7]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 81531DiisopropylethylamineHCID 1050975-Phenyl-2-pyridinamineHCID 58447644[4-(2-Methyl-pyridin-4-yl)-phenyl]-acetic acid

Product 1

HCID 469277262-(4-(2-methylpyridin-4-yl)phenyl)-N-(5-phenylpyridin-2-yl)acetamide

Sources & evidence

ORD record
ord-df854770173b4105be7034c9968a5d69
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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