Bromide ion → (6-methyl-1H-indol-3-yl)-(2,2,3,3-tetramethylcyclopropyl)methanone

HRID 2158506Notes

Reaction equation

HRID 2158506 reaction equation
[Br-:11].[CH2:12]([Mg+:13])[CH3:14].[CH3:15][C:16]1([CH3:24])[CH:17]([C:21](=[O:22])[Cl:23])[C:18]1([CH3:19])[CH3:20].[CH3:1][c:2]1[cH:3][cH:4][c:5]2[cH:6][cH:7][nH:8][c:9]2[cH:10]1.[Cl-:28].[Cl-:30].[Cl:25][CH2:26][Cl:27].[Zn+2:29]>>[CH3:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:21]([CH:17]3[C:16]([CH3:15])([CH3:24])[C:18]3([CH3:19])[CH3:20])=[O:22])[cH:7][nH:8][c:9]2[cH:10]1

Participants

8

Reactant 7

HCID 259Bromide ionHCID 312Chloride2×HCID 6344DichloromethaneHCID 32051Zinc(2+)HCID 1379281H-Indole, 6-methyl-HCID 110410022,2,3,3-Tetramethylcyclopropane-1-carbonyl chlorideHCID 178461628HCID 178461628, compound

Product 1

HCID 24823778(6-methyl-1H-indol-3-yl)-(2,2,3,3-tetramethylcyclopropyl)methanone

Sources & evidence

ORD record
ord-bcd80325145941d88487c9edcddc0491
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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