Tetrahydrofuran → (2-Amino-1-cyclohexyl-1H-benzimidazol-5-yl)methanol

HRID 2158754Notes

Reaction equation

HRID 2158754 reaction equation
[AlH4-:23].[Li+:22].[NH2:1][c:2]1[n:3][c:4]2[c:5]([n:6]1[CH:7]1[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12]1)[cH:13][cH:14][c:15]([C:17](=[O:18])[O:19][CH2:20][CH3:21])[cH:16]2.[O:24]1[CH2:25][CH2:26][CH2:27][CH2:28]1>>[NH2:1][c:2]1[n:3][c:4]2[c:5]([n:6]1[CH:7]1[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12]1)[cH:13][cH:14][c:15]([CH2:17][OH:18])[cH:16]2

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 10879Aluminate(1-), tetrahydro-, (T-4)-HCID 28486Lithium ionHCID 67254051Ethyl 2-amino-1-cyclohexyl-1H-benzo[d]imidazole-5-carboxylate

Product 1

HCID 67252967(2-Amino-1-cyclohexyl-1H-benzimidazol-5-yl)methanol

Sources & evidence

ORD record
ord-7c8cc01b3d6e409caf9311c47723b42e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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