Dimethylformamide → 7-chloro-3-(4-dipropylaminomethyl-thiazol-2-yl)-5-methyl-5,6-dihydro-4H-imidazo(1,5-a][1,4]benzodiazepin-6-one

HRID 2158925Notes

Reaction equation

HRID 2158925 reaction equation
[CH2:25]([CH2:26][CH3:27])[NH:28][CH2:29][CH2:30][CH3:31].[CH3:32][N:33]([CH3:34])[CH:35]=[O:36].[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]1[C:8](=[O:24])[N:9]([CH3:23])[CH2:10][c:11]1[n:12]-2[cH:13][n:14][c:15]1-[c:16]1[s:17][cH:18][c:19]([CH2:21][Cl:22])[n:20]1.[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1>>[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]1[C:8](=[O:24])[N:9]([CH3:23])[CH2:10][c:11]1[n:12]-2[cH:13][n:14][c:15]1-[c:16]1[s:17][cH:18][c:19]([CH2:21][N:28]([CH2:25][CH2:26][CH3:27])[CH2:29][CH2:30][CH3:31])[n:20]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 8902DipropylamineHCID 218423077-chloro-3-(4-chloromethyl-thiazol-2-yl)-5-methyl-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepin-6-one

Product 1

HCID 218422467-chloro-3-(4-dipropylaminomethyl-thiazol-2-yl)-5-methyl-5,6-dihydro-4H-imidazo(1,5-a][1,4]benzodiazepin-6-one

Sources & evidence

ORD record
ord-d3b6490d86f14a2182276ffa96944986
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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