Potassium Cation → 4-(4-Chloro-2-fluoroanilino)-7-(3-chloropropoxy)-6-methoxyquinazoline
Reaction equation
[Br:23][CH2:24][CH2:25][CH2:26][Cl:27].[C:28](=[O:29])([O-:30])[O-:31].[Cl:1][c:2]1[cH:3][c:4]([F:22])[c:5]([NH:6][c:7]2[n:8][cH:9][n:10][c:11]3[cH:12][c:13]([OH:19])[c:14]([O:17][CH3:18])[cH:15][c:16]23)[cH:20][cH:21]1.[K+:32].[K+:33].[O:34]=[CH:35][N:36]([CH3:37])[CH3:38].[OH2:39]>>[Cl:1][c:2]1[cH:3][c:4]([F:22])[c:5]([NH:6][c:7]2[n:8][cH:9][n:10][c:11]3[cH:12][c:13]([O:19][CH2:24][CH2:25][CH2:26][Cl:27])[c:14]([O:17][CH3:18])[cH:15][c:16]23)[cH:20][cH:21]1Participants
7
Sources & evidence
- ORD record
- ord-86649b2d88a744f787f1f39bd0c8e8cb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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