Hydrochloric Acid → 3-(2-Piperazin-1-yl-1,3-thiazol-4-yl)benzonitrile

HRID 2159507Notes

Reaction equation

HRID 2159507 reaction equation
[C:2](#[N:3])[c:4]1[cH:5][c:6](-[c:10]2[n:11][c:12]([N:15]3[CH2:16][CH2:17][N:18]([C:21]([O:22][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:27])[CH2:19][CH2:20]3)[s:13][cH:14]2)[cH:7][cH:8][cH:9]1.[CH3:28][CH2:29][O:30][C:31](=[O:32])[CH3:33].[ClH:1]>>[C:2](#[N:3])[c:4]1[cH:5][c:6](-[c:10]2[n:11][c:12]([N:15]3[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]3)[s:13][cH:14]2)[cH:7][cH:8][cH:9]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 8857Ethyl AcetateHCID 68779422Tert-butyl 4-[4-(3-cyanophenyl)-1,3-thiazol-2-yl]piperazine-1-carboxylate

Product 1

HCID 639931083-(2-Piperazin-1-yl-1,3-thiazol-4-yl)benzonitrile

Sources & evidence

ORD record
ord-38d686ffc6794986a2bcb17f491189a2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…