Hydrochloric Acid → Benzyl[4-(2-aminopyridin-4-yloxy)-2-fluorophenyl]carbamate

HRID 2159887Notes

Reaction equation

HRID 2159887 reaction equation
[C:34]([O:35][CH2:36][CH3:37])(=[O:38])[CH3:39].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[NH:11][c:12]1[c:13]([F:33])[cH:14][c:15]([O:16][c:17]2[cH:18][c:19]([NH:23][C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[n:20][cH:21][cH:22]2)[cH:31][cH:32]1.[ClH:40]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[NH:11][c:12]1[c:13]([F:33])[cH:14][c:15]([O:16][c:17]2[cH:18][c:19]([NH2:23])[n:20][cH:21][cH:22]2)[cH:31][cH:32]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 8857Ethyl AcetateHCID 57677355Tert-butyl [4-(4-benzyloxycarbonylamino-3-fluorophenoxy)pyridin-2-yl]carbamate

Product 1

HCID 57470855Benzyl[4-(2-aminopyridin-4-yloxy)-2-fluorophenyl]carbamate

Sources & evidence

ORD record
ord-ac58f82cf2c44de095ff26cce3edf4d0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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