Tetrahydrofuran → 4-bromo-5-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxylic Acid

HRID 2160439Notes

Reaction equation

HRID 2160439 reaction equation
[Br:9][c:10]1[cH:11][c:12]([C:21](=[O:22])[OH:23])[s:13][c:14]1-[c:15]1[cH:16][cH:17][n:18][n:19]1[CH3:20].[Cl:1][N:2]1[C:3](=[O:4])[CH2:5][CH2:6][C:7]1=[O:8].[O:24]1[CH2:25][CH2:26][CH2:27][CH2:28]1>>[Cl:1][c:16]1[c:15](-[c:14]2[c:10]([Br:9])[cH:11][c:12]([C:21](=[O:22])[OH:23])[s:13]2)[n:19]([CH3:20])[n:18][cH:17]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 31398ChlorosuccinimideHCID 578265674-bromo-5-(1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxylic Acid

Product 1

HCID 578266064-bromo-5-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxylic Acid

Sources & evidence

ORD record
ord-cbb32acf86244a6bb4d6e1b61dfeb8a3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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