Dimethylformamide → N-(3-Fluoro-4-methanesulfonylamino-benzyl)-3-[2-(3-hydroxy-pyrrolidin-1-yl)-6-trifluoromethyl-pyridin-3-yl]-acrylamide
Reaction equation
[CH3:41][CH2:42][O:43][C:44]([CH3:45])=[O:46].[Cl:1][c:2]1[n:3][c:4]([C:26]([F:27])([F:28])[F:29])[cH:5][cH:6][c:7]1[CH:8]=[CH:9][C:10](=[O:11])[NH:12][CH2:13][c:14]1[cH:15][c:16]([F:25])[c:17]([NH:20][S:21](=[O:22])(=[O:23])[CH3:24])[cH:18][cH:19]1.[NH:35]1[CH2:36][CH:37]([OH:40])[CH2:38][CH2:39]1.[O:30]=[CH:31][N:32]([CH3:33])[CH3:34]>>[c:2]1([N:35]2[CH2:36][CH:37]([OH:40])[CH2:38][CH2:39]2)[n:3][c:4]([C:26]([F:27])([F:28])[F:29])[cH:5][cH:6][c:7]1[CH:8]=[CH:9][C:10](=[O:11])[NH:12][CH2:13][c:14]1[cH:15][c:16]([F:25])[c:17]([NH:20][S:21](=[O:22])(=[O:23])[CH3:24])[cH:18][cH:19]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-94359f9c1455492ea3fd1b5f8b9d1374
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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