Hydrochloric Acid → (+/-)-1-[4-(2-Methylphenyl)-2,3-dihydro-1-benzofuran-2-yl]methanamine

HRID 2160708Notes

Reaction equation

HRID 2160708 reaction equation
[CH3:1][c:2]1[cH:3][cH:4][c:5]([S:6]([O:7][CH2:8][CH:9]2[CH2:10][c:11]3[c:12](-[c:13]4[cH:14][cH:15][cH:16][cH:17][c:18]4[CH3:19])[cH:20][cH:21][cH:22][c:23]3[O:24]2)(=[O:25])=[O:26])[cH:27][cH:28]1.[ClH:56].[N-:30]=[N+:31]=[N-:32].[N-:53]=[N+:54]=[N-:55].[N:33](=[N+:34]=[N-:35])[CH2:36][CH:37]1[O:38][c:39]2[c:40]([c:42](-[c:46]3[c:47]([CH3:52])[cH:48][cH:49][cH:50][cH:51]3)[cH:43][cH:44][cH:45]2)[CH2:41]1.[Na+:29]>>[NH2:33][CH2:36][CH:37]1[O:38][c:39]2[c:40]([c:42](-[c:46]3[c:47]([CH3:52])[cH:48][cH:49][cH:50][cH:51]3)[cH:43][cH:44][cH:45]2)[CH2:41]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 33558Azide2×HCID 86599075(+/-)-[4-(2-Methylphenyl)-2,3-dihydro-1-benzofuran-2-yl]methyl 4-methylbenzenesulfonateHCID 86599171(+/-)-2-(Azidomethyl)-4-(2-methylphenyl)-2,3-dihydro-1-benzofuran

Product 1

HCID 68961455(+/-)-1-[4-(2-Methylphenyl)-2,3-dihydro-1-benzofuran-2-yl]methanamine

Sources & evidence

ORD record
ord-b70b4187d8004af5afe0b04cc74bb945
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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