Acetate → 2-(3,4-difluorophenyl)-4-(2-hydroxy-2-methyl-1-propoxy)-5-[4-(aminosulfonyl)phenyl]-3(2H)-pyridazinone
Reaction equation
[C:47]([O-:48])(=[O:49])[CH3:50].[CH2:58]1[O:59][CH2:60][CH2:61][CH2:62]1.[CH3:33][Si:34]([N-:37][Si:35]([CH3:36])([CH3:38])[CH3:39])([CH3:40])[CH3:41].[F:1][c:2]1[cH:3][c:4](-[n:9]2[n:10][cH:11][c:12](-[c:22]3[cH:23][cH:24][c:25]([S:28](=[O:29])(=[O:30])[CH3:31])[cH:26][cH:27]3)[c:13]([O:16][CH2:17][C:18]([CH3:19])([CH3:20])[OH:21])[c:14]2=[O:15])[cH:5][cH:6][c:7]1[F:8].[NH2:52][O:53][S:54]([OH:55])(=[O:56])=[O:57].[Na+:32].[Na+:43].[Na+:51].[OH-:42].[OH2:44].[OH2:45].[OH2:46].[OH2:63]>>[F:1][c:2]1[cH:3][c:4](-[n:9]2[n:10][cH:11][c:12](-[c:22]3[cH:23][cH:24][c:25]([S:28](=[O:29])(=[O:30])[NH2:37])[cH:26][cH:27]3)[c:13]([O:16][CH2:17][C:18]([CH3:19])([CH3:20])[OH:21])[c:14]2=[O:15])[cH:5][cH:6][c:7]1[F:8]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-e2f69f9590b44665bae311297b22009b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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