Dichloromethane → 4-chloro-N-(5,5-difluoro-2-oxoazepan-3-yl)benzenesulfonamide

HRID 2161195Notes

Reaction equation

HRID 2161195 reaction equation
[Cl:16][c:17]1[cH:18][cH:19][c:20]([S:23](=[O:24])(=[O:25])[NH:26][CH:27]2[C:28](=[O:47])[N:29]([CH2:36][c:37]3[cH:38][cH:39][c:40]([O:41][CH3:42])[cH:43][c:44]3[O:45][CH3:46])[CH2:30][CH2:31][C:32]([F:34])([F:35])[CH2:33]2)[cH:21][cH:22]1.[Cl:48][CH2:49][Cl:50].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7].[OH:8][S:9]([C:10]([F:11])([F:12])[F:13])(=[O:14])=[O:15]>>[Cl:16][c:17]1[cH:18][cH:19][c:20]([S:23](=[O:24])(=[O:25])[NH:26][CH:27]2[C:28](=[O:47])[NH:29][CH2:30][CH2:31][C:32]([F:34])([F:35])[CH2:33]2)[cH:21][cH:22]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 62406Trifluoromethanesulfonic acidHCID 68624910HCID 68624910, compound

Product 1

HCID 686250364-chloro-N-(5,5-difluoro-2-oxoazepan-3-yl)benzenesulfonamide

Sources & evidence

ORD record
ord-61c0bc41b51f46d8aafa2903e91b7a9d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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