Water → 1-(2,2,3,4,6,7-Hexamethyl-3-hydroxy-2,3-dihydro-1-benzofuran-5-yl)-4-(4-methoxyphenyl)piperazine
Reaction equation
[CH2:1]([O:2][CH2:3][CH3:4])[CH3:5].[CH3:13][O:14][c:15]1[cH:16][cH:17][c:18]([N:21]2[CH2:22][CH2:23][N:24]([c:27]3[c:28]([CH3:41])[c:29]([CH3:40])[c:30]4[c:31]([c:38]3[CH3:39])[C:32](=[O:37])[C:33]([CH3:35])([CH3:36])[O:34]4)[CH2:25][CH2:26]2)[cH:19][cH:20]1.[CH3:42][CH2:43][O:44][C:45](=[O:46])[CH3:47].[CH3:6][Li:7].[O:8]1[CH2:9][CH2:10][CH2:11][CH2:12]1.[OH2:48]>>[CH3:1][C:32]1([OH:37])[c:31]2[c:30]([c:29]([CH3:40])[c:28]([CH3:41])[c:27]([N:24]3[CH2:23][CH2:22][N:21]([c:18]4[cH:17][cH:16][c:15]([O:14][CH3:13])[cH:20][cH:19]4)[CH2:26][CH2:25]3)[c:38]2[CH3:39])[O:34][C:33]1([CH3:35])[CH3:36]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-da589684206942318aba3b352f0ce6b6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…