Methyl iodide → 1-(4-Benzylpiperazin-1-yl)-3-methyltetrahydropyrimidin-2(1H)-one
Reaction equation
[CH2:11]([c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1)[N:18]1[CH2:19][CH2:20][N:21]([N:24]2[C:25](=[O:30])[NH:26][CH2:27][CH2:28][CH2:29]2)[CH2:22][CH2:23]1.[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:1][Si:2]([N-:3][Si:4]([CH3:5])([CH3:6])[CH3:7])([CH3:8])[CH3:9].[CH3:31][I:32].[Li+:10]>>[CH2:11]([c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1)[N:18]1[CH2:19][CH2:20][N:21]([N:24]2[C:25](=[O:30])[N:26]([CH3:31])[CH2:27][CH2:28][CH2:29]2)[CH2:22][CH2:23]1Participants
6
Sources & evidence
- ORD record
- ord-364b234e3fcf47639d26a02b5e374f94
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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