Nitrogen → 3-[[5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-2-oxo-1,3-oxazolidin-3-yl]methyl]-4-(4-fluoro-2-methoxy-5-propan-2-ylphenyl)benzonitrile
Reaction equation
[CH3:47][N:48]([CH3:49])[CH:50]=[O:51].[Cu:42][C:43]#[N:44].[F:1][C:2]([c:3]1[cH:4][c:5]([CH:13]2[CH:14]([CH3:39])[N:15]([CH2:19][c:20]3[c:21](-[c:27]4[c:28]([O:37][CH3:38])[cH:29][c:30]([F:36])[c:31]([CH:33]([CH3:34])[CH3:35])[cH:32]4)[cH:22][cH:23][c:24]([Br:26])[cH:25]3)[C:16](=[O:18])[O:17]2)[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:40])[F:41].[N:45]#[N:46].[cH:52]1[cH:53][cH:54][c:55]([P:56]([Pd:57]([P:58]([c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)([c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)[c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)([P:77]([c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)([c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)[c:90]2[cH:91][cH:92][cH:93][cH:94][cH:95]2)[P:96]([c:97]2[cH:98][cH:99][cH:100][cH:101][cH:102]2)([c:103]2[cH:104][cH:105][cH:106][cH:107][cH:108]2)[c:109]2[cH:110][cH:111][cH:112][cH:113][cH:114]2)([c:115]2[cH:116][cH:117][cH:118][cH:119][cH:120]2)[c:121]2[cH:122][cH:123][cH:124][cH:125][cH:126]2)[cH:127][cH:128]1>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH:13]2[CH:14]([CH3:39])[N:15]([CH2:19][c:20]3[c:21](-[c:27]4[c:28]([O:37][CH3:38])[cH:29][c:30]([F:36])[c:31]([CH:33]([CH3:34])[CH3:35])[cH:32]4)[cH:22][cH:23][c:24]([C:43]#[N:44])[cH:25]3)[C:16](=[O:18])[O:17]2)[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:40])[F:41]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-7fe990fbd2fa4f18ac3dae623a5c7d17
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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