1,2-Dichloroethane → 5-benzyl-2,4-dichloro-5H-pyrrolo[3,2-d]pyrimidine

HRID 2162414Notes

Reaction equation

HRID 2162414 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[cH:9][cH:10][c:11]2[n:12][c:13]([NH2:18])[n:14][c:15]([Cl:17])[c:16]12.[Cl:27][CH2:28][CH2:29][Cl:30].[N:19]([O:20][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:25].[OH2:26]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[cH:9][cH:10][c:11]2[n:12][c:13]([Cl:27])[n:14][c:15]([Cl:17])[c:16]12

Participants

5

Reactant 4

HCID 111,2-DichloroethaneHCID 962WaterHCID 10906Tert-Butyl nitriteHCID 576936175-benzyl-4-chloro-5H-pyrrolo[3,2-d]pyrimidin-2-amine

Product 1

HCID 147277655-benzyl-2,4-dichloro-5H-pyrrolo[3,2-d]pyrimidine

Sources & evidence

ORD record
ord-45d2ab85cedc407fb91de8bb828cbc1d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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