Acetyl chloride → HCID 22754119, compound

HRID 2163154Notes

Reaction equation

HRID 2163154 reaction equation
[NH2:1][C:2]1[C:3]([I:20])=[C:4]([C:13]([NH:15][CH2:16][CH:17]([OH:19])[CH3:18])=[O:14])[C:5]([I:12])=[C:6]([C:10]=1[I:11])[C:7]([OH:9])=[O:8].[C:21](Cl)(=[O:23])[CH3:22]>CC(N(C)C)=O>[C:21]([NH:1][C:2]1[C:3]([I:20])=[C:4]([C:13]([NH:15][CH2:16][CH:17]([OH:19])[CH3:18])=[O:14])[C:5]([I:12])=[C:6]([C:10]=1[I:11])[C:7]([OH:9])=[O:8])(=[O:23])[CH3:22]

Participants

4

Reactant 2

HCID 6367Acetyl chlorideHCID 22754106HCID 22754106, compound

Product 1

HCID 22754119HCID 22754119, compoundYield 87%

Reagents, catalysts & solvents 1

HCID 31374DimethylacetamideSolvent

Procedure

Analogously to Example 3, 5-amino-N-(2-hydroxypropyl)2,4,6-triiodoisophthalamic acid and acetyl chloride are reacted in dimethylacetamide. Yield: 87%, m.p. 276°-278° C., with decomposition.

Sources & evidence

ORD record
ord-74a6df7704f74dff92fb48715cb35e35
Source dataset
uspto-grants-1979_01
Patent number
US04132731

Reaction notes

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