Methyl p-toluenesulfonate → HCID 22754352, compound

HRID 2163221Notes

Reaction equation

HRID 2163221 reaction equation
[C:1]([NH:4][C:5]1[N:6]=[C:7]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[S:8][CH:9]=1)(=[O:3])[CH3:2].S(C1C=CC(C)=CC=1)(O[CH3:20])(=O)=O.[H-].[Na+]>C(#N)C>[C:1]([N:4]([C:5]1[N:6]=[C:7]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[S:8][CH:9]=1)[CH3:20])(=[O:3])[CH3:2]

Participants

5

Reactant 3

HCID 6645Methyl p-toluenesulfonateHCID 24758Sodium hydrideHCID 12229027HCID 12229027, compound

Product 1

HCID 22754352HCID 22754352, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

A mixture of 4-acetamido-2-phenylthiazole, prepared according to Example 1, and methyl tosylate in acetonitrile may be treated with sodium hydride to give the title compound.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-fd67985237174d5a866bc1187a510953
Source dataset
uspto-grants-1979_01
Patent number
US04132798

Reaction notes

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