Diethylamine → HCID 21333309, compound

HRID 2163340Notes

Reaction equation

HRID 2163340 reaction equation
C(CO[C:5](=[O:31])[C:6]1[CH:11]=[CH:10][C:9]([C:12]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[CH:8][N:7]=1)#N.[CH2:32]([NH:34][CH2:35][CH3:36])[CH3:33]>O>[CH2:32]([N:34]([CH2:35][CH3:36])[C:5](=[O:31])[C:6]1[CH:11]=[CH:10][C:9]([C:12]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)([C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)[C:25]2[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=2)=[CH:8][N:7]=1)[CH3:33]

Participants

4

Reactant 2

HCID 8021DiethylamineHCID 21333313HCID 21333313, compound

Product 1

HCID 21333309HCID 21333309, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Heat at reflux for 6 hours a mixture of 0.1 mole of cyanomethyl-5-(triphenylmethyl)-picolinate and 0.5 moles of diethylamine. Cool the reaction mixture, pour into water and extract with chloroform. Dry the chloroform layer over anhydrous sodium sulfate and evaporate to obtain thereby the product of this example.

Workup

  1. temperatureHeat
  2. temperatureat reflux for 6 hours
  3. temperatureCool the reaction mixture
  4. extractionextract with chloroform
  5. dry with materialDry the chloroform layer over anhydrous sodium sulfate
  6. customevaporate
  7. customto obtain

Sources & evidence

ORD record
ord-0aae57147389469f82a1e3c02086eb76
Source dataset
uspto-grants-1979_01
Patent number
US04133887

Reaction notes

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