Ammonia → HCID 22752003, compound

HRID 2163473Notes

Reaction equation

HRID 2163473 reaction equation
[CH2:1]([CH:3]1[C:7](=[O:8])[C:6]([S:9]CC2C=CC=CC=2)=[C:5]([CH2:17][CH3:18])[O:4]1)[CH3:2].[Na].N>CCOCC>[CH2:1]([CH:3]1[C:7](=[O:8])[CH:6]([SH:9])[CH:5]([CH2:17][CH3:18])[O:4]1)[CH3:2]

Participants

5

Reactant 3

HCID 222AmmoniaHCID 5360545SodiumHCID 22752000HCID 22752000, compound

Product 1

HCID 22752003HCID 22752003, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A solution of 1.4 g of 2,5-diethyl-4-benzylthio-2,3-dihydrofuran-3-one in 50 ml anhydrous ether was treated with 0.88 g of sodium in liquid ammonia as described in Example A7. After working up the reaction mixture the title compound could be isolated by preparative gaschromatography. Relative retention time as compared with 43.1 minutes for dodecane was 51.9 minutes.

Sources & evidence

ORD record
ord-504a746d915746879ac9f0e2fd0f86fa
Source dataset
uspto-grants-1979_01
Patent number
US04134901

Reaction notes

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