2-Aminopyridine → HCID 54684958, compound

HRID 2164096Notes

Reaction equation

HRID 2164096 reaction equation
[CH2:1]([N:3]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[C:5]2[S:12](=[O:23])(=[O:22])[N:13]([CH3:21])[C:14]([C:17](OC)=[O:18])=[C:15]([OH:16])[C:4]1=2)[CH3:2].[NH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][N:26]=1>C1(C)C(C)=CC=CC=1>[CH2:1]([N:3]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[C:5]2[S:12](=[O:23])(=[O:22])[N:13]([CH3:21])[C:14]([C:17]([NH:24][C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][N:26]=3)=[O:18])=[C:15]([OH:16])[C:4]1=2)[CH3:2]

Participants

4

Reactant 2

HCID 104392-AminopyridineHCID 54684933HCID 54684933, compound

Product 1

HCID 54684958HCID 54684958, compoundYield 72%

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

5-Ethyl-2,5-dihydro-4-hydroxy-2-methyl-N-(2-pyridyl)-1,2 thiazino[5,6-b]indole-3-carboxamide 1,1-dioxide was prepared analogous to Example 15 from methyl 5-ethyl-2,5-dihydro-4-hydroxy-2-methyl-1,2-thiazino[5,6-b]indole-3-carboxylate-1,1-dioxide and 2-amino-pyridine with a yield of 72% of theory. M.p.: 232° C. (decomposition, from xylene).

Sources & evidence

ORD record
ord-264aa67a99e64daea8c47ea232012093
Source dataset
uspto-grants-1979_01
Patent number
US04137313

Reaction notes

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