Aniline → HCID 54684971, compound

HRID 2164097Notes

Reaction equation

HRID 2164097 reaction equation
[CH2:1]([N:3]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[C:5]2[S:12](=[O:23])(=[O:22])[N:13]([CH3:21])[C:14]([C:17]([O:19]C)=O)=[C:15]([OH:16])[C:4]1=2)[CH3:2].[NH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>C1(C)C(C)=CC=CC=1>[CH2:1]([N:3]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[C:5]2[S:12](=[O:23])(=[O:22])[N:13]([CH3:21])[C:14]([C:17]([NH:24][C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)=[O:19])=[C:15]([OH:16])[C:4]1=2)[CH3:2]

Participants

4

Reactant 2

HCID 6115AnilineHCID 54684933HCID 54684933, compound

Product 1

HCID 54684971HCID 54684971, compoundYield 56%

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

5-Ethyl-2,5-dihydro-4-hydroxy-2-methyl-N-phenyl-1,2-thiazino-[5,6-b]indole-3-carboxamide-1,1-dioxide was prepared analogous to Example 15 from methyl 5-ethyl-2,5-dihydro-4-hydroxy-2-methyl-1,2-thiazino[5,6-b]indole-3-carboxylate-1,1-dioxide and aniline a yield of 56% of theory. M.p.: 268° C. (decomposition; from xylene).

Sources & evidence

ORD record
ord-6cae755bc8e1494d805b7aabcce285e9
Source dataset
uspto-grants-1979_01
Patent number
US04137313

Reaction notes

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