反应详情

Seventeen grams (0.05 mole) of sodium 2-amino-3-(4-methylthiobenzoyl)phenylacetic acid monohydrate are dissolved in approximately 150 ml of dimethylformamide and the solution treated with 33 g ethyl iodide. The solution is stirred at room temperature for 2.5 hrs. and added to water and the mixture extracted several times with benzene. The combined benzene extracts are washed with dilute base and water, dried over sodium sulfate and concentrated to obtain the titled compound.

1. extractionthe mixture extracted several times with benzene
2. washThe combined benzene extracts are washed
3. additionwith dilute base and water
4. dry with materialdried over sodium sulfate
5. concentrationconcentrated