3-Chloro-N,N-dimethyl-1-propanamine → HCID 13135882, compound

HRID 2164535Notes

Reaction equation

HRID 2164535 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12]([NH2:13])=[C:11]([C:14]([O:16][CH2:17][CH2:18][CH2:19][CH3:20])=[O:15])[N:10]=[N:9]2)=[CH:4][CH:3]=1.[Cl:21][CH2:22][CH2:23][CH2:24][N:25]([CH3:27])[CH3:26]>CN(C)C=O>[ClH:21].[CH3:26][N:25]([CH3:27])[CH2:24][CH2:23][CH2:22][N:9]1[N:10]=[C:11]([C:14]([O:16][CH2:17][CH2:18][CH2:19][CH3:20])=[O:15])[C:12]([NH:8][C:5]2[CH:6]=[CH:7][C:2]([Br:1])=[CH:3][CH:4]=2)=[N:13]1

Participants

4

Reactant 2

HCID 669603-Chloro-N,N-dimethyl-1-propanamineHCID 13135869HCID 13135869, compound

Product 1

HCID 13135882HCID 13135882, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A mixture consisting of 8.5 gm (0.025 mol) of n-butyl 1-(4-bromophenyl)-5-amino-1H-1,2,3-triazole-4-carboxylate, 100 ml of absolute dimethylformamide and 9.1 gm (0.075 mol) of 1-chloro-3-(N,N-dimethylamino)-propane was reacted and worked up as in Example 1. 1.5. gm of the desired compound were obtained, corresponding to 13% of theory, with a melting point of 158° C.

Workup

  1. customwas reacted

Sources & evidence

ORD record
ord-4d6764bf6bfe4e6584b5386a14170e6b
Source dataset
uspto-grants-1985_03
Patent number
US04505912

Reaction notes

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