Potassium Hydroxide → HCID 13281343, compound

HRID 2164840Notes

Reaction equation

HRID 2164840 reaction equation
[Cl:1][C:2]1[C:13]2[CH2:12][CH2:11][CH2:10][C:9](=O)[C:8]3[CH:15]=[CH:16][CH:17]=[CH:18][C:7]=3[C:6]=2[CH:5]=[CH:4][CH:3]=1.O.NN.[OH-].[K+]>C(O)CO>[Cl:1][C:2]1[C:13]2[CH2:12][CH2:11][CH2:10][CH2:9][C:8]3[CH:15]=[CH:16][CH:17]=[CH:18][C:7]=3[C:6]=2[CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 14797Potassium HydroxideHCID 24654Hydrazine hydrate (1:1)HCID 13281350HCID 13281350, compound

Product 1

HCID 13281343HCID 13281343, compoundYield 90.6%

Reagents, catalysts & solvents 1

HCID 174Ethylene GlycolSolvent

Procedure

The reaction of 9-chloro-5,6,7,8-tetrahydrodibenzo[a,c]cycloocten-5-one (3.0 g, 0.015 mole), 85% hydrazine hydrate (4.5 g, 0.076 mole), potassium hydroxide (3.0 g, 0.046 mole) and ethylene glycol (39 ml) produced an oil. The oil was purified by column chromatography on silica gel, eluted with toluene to yield 4-chloro-5,6,7,8-tetrahydrodibenzo[a,c]cyclooctene as an oil (3.3 grams).

Workup

  1. customproduced an oil
  2. customThe oil was purified by column chromatography on silica gel
  3. washeluted with toluene

Sources & evidence

ORD record
ord-e1083872b7e54aca91255755fa833b02
Source dataset
uspto-grants-1985_03
Patent number
US04507317

Reaction notes

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