HRID2165651

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCOC(=O)c1cn(CC)c2c(F)c(F)c(F)cc2c1=O

HCID5140913

Ethyl 1-ethyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate

C14H12F3NO3

PRODUCTS

生成物

结构：CCn1cc(C(=O)O)c(=O)c2cc(F)c(F)c(F)c21

HCID9835179

1-Ethyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

C12H8F3NO3

收率 62.3%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID313

Hydrochloric Acid

ClH

PROCEDURE

实验过程

A mixture of 17.7 g of the above ester was refluxed in 150 ml of 37% hydrochloric acid for 2 hours, giving 10 g of 1-ethyl-1,4-dihydro-6,7,8-trifluoro-4-oxo-3-quinolinecarboxylic acid, mp 240° C. (dec.).