反应详情

44 g of 5-nitro-2-chlorobenzenesulfonyl chloride and 100 ml of. dichloromethane were blended, and a dichloromethane solution containing 48.4 g of methyloctadecylamine and 36.1 ml of triethylamine was added dropwise thereto. After completion of the reaction, the reaction solvent was removed by distillation under reduced pressure. 300 ml of methanol was added to the residue and dissolved, and then the resulting solution was gradually cooled to precipitate a crystal. The crystal was taken out by filtration and dried. Yield: 64 g, 74%.

1. additionwas added dropwise
2. customAfter completion of the reaction
3. customthe reaction solvent was removed by distillation under reduced pressure
4. addition300 ml of methanol was added to the residue
5. dissolutiondissolved
6. temperaturethe resulting solution was gradually cooled
7. customto precipitate a crystal
8. filtrationThe crystal was taken out by filtration
9. customdried