反应详情

A mixture of 329 mg (0.001 mol) of 3-cyano-4-methoxymethyl-5-phenoxy-beta-carboline, 100 mg of hydroxylamine hydrochloride, 20 ml of ethanol (99%) and 0.52 ml of a 20% aqueous potassium carbonate solution is refluxed for 22 hours. The reaction mixture is filtered and the filtrate concentrated. The residue is mixed with 10 ml of water, the crystalline solid is filtered off and washed with water.

1. temperatureis refluxed for 22 hours
2. filtrationThe reaction mixture is filtered
3. concentrationthe filtrate concentrated
4. additionThe residue is mixed with 10 ml of water
5. filtrationthe crystalline solid is filtered off
6. washwashed with water