Isoamylamine → HCID 13150832, compound

HRID 2166593Notes

Reaction equation

HRID 2166593 reaction equation
[O:1]1[CH:6]([C:7]([OH:9])=[O:8])[CH:2]1[C:3]([OH:5])=O.[CH2:10]([K])[CH3:11].C(Cl)(=O)C(Cl)=O.[CH2:19]([NH2:24])[CH2:20][CH:21]([CH3:23])[CH3:22]>>[CH2:19]([NH:24][C:3](=[O:5])[CH:2]1[O:1][CH:6]1[C:7]([O:9][CH2:10][CH3:11])=[O:8])[CH2:20][CH:21]([CH3:23])[CH3:22]

Participants

4

Reactant 3

HCID 7894IsoamylamineHCID 65578Oxalyl chlorideHCID 178461626HCID 178461626, compound

Product 1

HCID 13150832HCID 13150832, compoundYield 52.4%

Procedure

Following the procedure of Example 1, monoethyl potassium epoxysuccinate (1.5 g) was successively treated with oxalyl chloride (1.04 g) and isoamylamine (2.3 g) to give 0.9 g of ethyl N-isoamyl-2,3-epoxysuccinamate (Compound No. 17) as colorless needles melting at 59°-61° C.

Sources & evidence

ORD record
ord-802b364ba85b47c38372f0b276ab8c77
Source dataset
uspto-grants-1983_06
Patent number
US04387238

Reaction notes

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