N-Methylcyclohexylamine → HCID 13150840, compound

HRID 2166599Notes

Reaction equation

HRID 2166599 reaction equation
[O:1]1[CH:6]([C:7]([OH:9])=[O:8])[CH:2]1[C:3]([OH:5])=O.[CH2:10]([K])[CH3:11].C(Cl)(=O)C(Cl)=O.[CH3:19][NH:20][CH:21]1[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]1>>[CH3:19][N:20]([CH:21]1[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]1)[C:3](=[O:5])[CH:2]1[O:1][CH:6]1[C:7]([O:9][CH2:10][CH3:11])=[O:8]

Participants

4

Reactant 3

HCID 7514N-MethylcyclohexylamineHCID 65578Oxalyl chlorideHCID 178461626HCID 178461626, compound

Product 1

HCID 13150840HCID 13150840, compoundYield 50.2%

Procedure

Following the procedure of Example 1, monoethyl potassium epoxysuccinate (1.0 g) was successively treated with oxalyl chloride (0.75 g) and N-methylcyclohexylamine (1.15 g) to give 0.64 g of ethyl N-methyl-N-cyclohexyl-2,3-epoxysuccinamate (Compound No. 31) as colorless needles melting at 52°-55° C.

Sources & evidence

ORD record
ord-46e7f64e9a674477ae115beb55b9c219
Source dataset
uspto-grants-1983_06
Patent number
US04387238

Reaction notes

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