Diethylamine → HCID 20499843, compound

HRID 2166604Notes

Reaction equation

HRID 2166604 reaction equation
[O:1]1[CH:6]([C:7]([OH:9])=[O:8])[CH:2]1[C:3]([OH:5])=O.[CH2:10]([K])[CH3:11].C(Cl)(=O)C(Cl)=O.[CH2:19]([NH:21][CH2:22][CH3:23])[CH3:20]>>[CH2:19]([N:21]([CH2:22][CH3:23])[C:3](=[O:5])[CH:2]1[O:1][CH:6]1[C:7]([O:9][CH2:10][CH3:11])=[O:8])[CH3:20]

Participants

4

Reactant 3

HCID 8021DiethylamineHCID 65578Oxalyl chlorideHCID 178461626HCID 178461626, compound

Product 1

HCID 20499843HCID 20499843, compoundYield 63.3%

Procedure

Following the procedure of Example 34, monoethyl potassium epoxysuccinate (1.0 g) was successively treated with oxalyl chloride (0.75 g) and diethylamine (0.74 g) to give 0.68 g of ethyl N,N-diethyl-2,3-epoxysuccinamate (Compound No. 57) as colorless oil.

Sources & evidence

ORD record
ord-a6b511759c5e4d4f900f9ee9efd3b048
Source dataset
uspto-grants-1983_06
Patent number
US04387238

Reaction notes

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