huagongshe.com
HRID2168161

反应详情

EQUATION

反应方程式

HRID 2168161 的结构方程式

REACTANTS

反应物

3
结构：FC(F)(Br)Br
HCID6382

Dibromodifluoromethane

CBr2F2

结构：c1ccc(P(c2ccccc2)c2ccccc2)cc1
HCID11776

Triphenylphosphine

C18H15P

结构：CC(C)(C)[Si](C)(C)O[C@@H]1CO[C@@H]2C(=O)CO[C@@H]21
HCID67049238

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)[Si](C)(C)O[C@@H]1CO[C@@H]2C(=C(F)F)CO[C@@H]21
HCID67048710

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(=O)N(C)C
溶剂HCID31374

Dimethylacetamide

C4H9NO

PROCEDURE

实验过程

Alternatively, ketone (87) may be treated with triphenylphosphine and dibromodifluoromethane in N,N-dimethylacetamide to give tert-butyl((3R,3aS,6aR)-6-(difluoromethylene)hexahydrofuro[3,2-b]furan-3-yloxy)dimethylsilane (97) as detailed in Scheme 8.