m-Chloroperbenzoic acid → HCID 178526230, compound

HRID 2171234Notes

Reaction equation

HRID 2171234 reaction equation
C1C=C(Cl)C=C(C(OO)=[O:9])C=1.[Br:12][C:13]1[CH:18]=[N:17][CH:16]=[C:15]2[NH:19][N:20]=[CH:21][C:14]=12>C(Cl)(Cl)Cl>[Br:12][C:13]1[CH:18]=[N+:17]([O-:9])[CH:16]=[C:15]2[NH:19][N:20]=[CH:21][C:14]=12

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 469162474-Bromo-1H-pyrazolo[3,4-c]pyridine

Product 1

HCID 178526230HCID 178526230, compoundYield 69.5%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

mCPBA (270 mg) was added to a CHCl3 (5 ml) suspension containing 4-bromo-1H-pyrazolo[3,4-c]pyridine (197 mg), followed by stirring at room temperature for 10 minutes. IPE (10 ml) was added to the reaction solution and a solid precipitate was collected by filtration. A white solid of 4-bromo-1H-pyrazolo[3,4-c]pyridine 6-oxide (148 mg) was thus obtained.

Workup

  1. additionIPE (10 ml) was added to the reaction solution
  2. filtrationa solid precipitate was collected by filtration

Sources & evidence

ORD record
ord-88ff4c10f8a84eb1b8710dbc067a4285
Source dataset
uspto-grants-2015_06
Patent number
US09051310B2

Reaction notes

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