Benzyl Bromide → HCID 86686198, compound

HRID 2171622Notes

Reaction equation

HRID 2171622 reaction equation
[O:1]1[CH2:6][CH2:5][CH:4]([CH2:7][O:8][C:9]2[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=2)[CH2:3][CH2:2]1.[CH2:15]([Br:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>C1COCC1>[Br-:22].[CH2:15]([N+:12]1[CH:13]=[CH:14][C:9]([O:8][CH2:7][CH:4]2[CH2:5][CH2:6][O:1][CH2:2][CH2:3]2)=[CH:10][CH:11]=1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

4

Reactant 2

HCID 7498Benzyl BromideHCID 68309841HCID 68309841, compound

Product 1

HCID 86686198HCID 86686198, compoundYield 91.6%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

4-(Tetrahydro-2H-pyran-4-ylmethoxy)pyridine (1.1 g) was mixed with THF (12 ml), and benzyl bromide (1.4 g) was added thereto, followed by stirring at room temperature overnight. The precipitated solid was collected by filtration to obtain 1-benzyl-4-(tetrahydro-2H-pyran-4-ylmethoxy)pyridinium bromide (1.9 g).

Workup

  1. additionwas added
  2. filtrationThe precipitated solid was collected by filtration

Sources & evidence

ORD record
ord-99782f593add4b838af43c71a02567e6
Source dataset
uspto-grants-2015_06
Patent number
US09051283B2

Reaction notes

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