反应详情

To a stirred solution of Pd2(dba)3 (0.52 g, 0.57 mmol) in o-xylene (140 mL), 2-dicyclohexylphosphino-2′,6′-dimethoxybiphenyl (0.94 g, 2.3 mmol) was added and degassed with nitrogen for 15 minutes. Carbazole (5.33 g, 31.9 mmol) and 2-bromotriphenylene (7.0 g, 22.7 mmol), sodium tert-butoxide (6.57 g, 68.3 mmol) were added and degassed with nitrogen for another 15 minutes. The reaction was refluxed for 2 days. The reaction mixture was filtered through silica, washed with DCM and dried under vacuum. Silica gel chromatography with 10% DCM/hexane, yielded 4.98 g of a while solid (56%) as the product.

1. customdegassed with nitrogen for 15 minutes
2. customdegassed with nitrogen for another 15 minutes
3. temperatureThe reaction was refluxed for 2 days
4. filtrationThe reaction mixture was filtered through silica
5. washwashed with DCM
6. customdried under vacuum