m-Chloroperbenzoic acid → HCID 86644563, compound

HRID 2174721Notes

Reaction equation

HRID 2174721 reaction equation
[Cl:1][C:2]1[S:6][C:5]([C:7]([NH:9][C:10]2([C:15]([O:17][CH3:18])=[O:16])[CH2:14][CH:13]=[CH:12][CH2:11]2)=[O:8])=[CH:4][CH:3]=1.ClC1C=CC=C(C(OO)=[O:27])C=1>C(Cl)Cl>[Cl:1][C:2]1[S:6][C:5]([C:7]([NH:9][C:10]2([C:15]([O:17][CH3:18])=[O:16])[CH2:14][CH:13]3[O:27][CH:12]3[CH2:11]2)=[O:8])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 68485462HCID 68485462, compound

Product 1

HCID 86644563HCID 86644563, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A mixture of 0.85 g (2.9 mmol) methyl 1-[(5-chloro-thiophen-2-yl)-carbonylamino]-cyclopent-3-ene-1-carboxylate and 20 ml methylene chloride is combined with 0.92 g 70% meta-chloroperbenzoic acid at 0° C. and stirred for 3 h at room temperature. The mixture is washed with sat. Sodium hydrogen carbonate solution and concentrated.

Workup

  1. washThe mixture is washed with sat. Sodium hydrogen carbonate solution
  2. concentrationconcentrated

Sources & evidence

ORD record
ord-ea0457bc56a34c25b86cdef843491469
Source dataset
uspto-grants-2015_06
Patent number
US09062034B2

Reaction notes

Loading…