Hydrochloric Acid → HCID 90413940, compound

HRID 2175964Notes

Reaction equation

HRID 2175964 reaction equation
[CH3:1][N:2]([CH3:13])[C:3]1[C:4]([C:10](N)=[O:11])=[N:5][C:6]([CH3:9])=[CH:7][CH:8]=1.[OH-:14].[K+].Cl>CCO>[CH3:1][N:2]([CH3:13])[C:3]1[C:4]([C:10]([OH:14])=[O:11])=[N:5][C:6]([CH3:9])=[CH:7][CH:8]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14797Potassium HydroxideHCID 90411801HCID 90411801, compound

Product 1

HCID 90413940HCID 90413940, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
90 °C

Procedure

To the title compound of Step A (91 mg, 0.5 mmol) in EtOH (1 mL) was added 4M KOH (0.5 μL). The reaction was then heated at 90° C. for 18 h. The reaction was then cooled to rt, acidified with 1N HCl (aq) to pH=3, concentrated and used without further purification in the next step.

Workup

  1. temperatureThe reaction was then cooled to rt
  2. concentrationconcentrated
  3. customused without further purification in the next step

Sources & evidence

ORD record
ord-2aedd6f016fc447a96e9355a486875d0
Source dataset
uspto-grants-2015_06
Patent number
US09062078B2

Reaction notes

Loading…